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Publication numberCN100506163 C
Publication typeGrant
Application numberCN 200410078545
Publication date1 Jul 2009
Filing date9 Sep 2004
Priority date9 Sep 2003
Also published asCN1623513A, DE102004043600A1, US7037265, US20050054925
Publication number200410078545.0, CN 100506163 C, CN 100506163C, CN 200410078545, CN-C-100506163, CN100506163 C, CN100506163C, CN200410078545, CN200410078545.0
Inventors史蒂文米勒, 李亚东, 理查德奇奥, 郝晓辉
ApplicantGe医药系统环球科技公司
Export CitationBiBTeX, EndNote, RefMan
External Links: SIPO, Espacenet
Method and apparatus for tissue harmonic imaging with natural (tissue) decoded coded excitation
CN 100506163 C
Abstract  translated from Chinese
本发明关于使用超声波机器提供组织谐波成像的方法(200、300、400、500)和装置(10)。 The present invention relates to the use of ultrasound machines to provide tissue harmonic imaging method (200, 300) and means (10). 具有大于1的时间带宽乘积的编码脉冲(210、310、410、510)和所述编码脉冲的反相型式(230、330、430、530)被发射到组织内。 Having the encoder pulse is greater than the time-bandwidth product of 1 (210,310,410,510) and inverting the encoder pulse pattern (230,330,430,530) is transmitted to the organization. 接收反向散射回波(220、240、320、340、420、440、520、540),并且在相干求和之前或之后进行滤波。 Receiving backscattered echo (220,240,320,340,420,440,520,540), and prior to or after filtering the coherent summation. 通过具体指定的超宽带(80%)波形在组织内的传播和脉冲反转来自然实现编码脉冲的接收回波的解码/压缩。 Specify by ultra-wideband (80%) and pulse wave propagation within the organization to naturally achieve reversal of decoding the received coded pulse echo / compression. 不需要昂贵的解码/压缩滤波器。 No expensive decoding / compression filter.
Claims(9)  translated from Chinese
1. 一种不使用匹配解码和压缩滤波器进行谐波成像的方法(200、300、400、500),包括下列步骤:发射具有大于1的时间带宽乘积的编码脉冲(210、310、410、510)和所述编码脉冲的反相型式(230、330、430、530);接收所述编码脉冲的至少一个反向散射回波(220、320、420、520)和所述编码脉冲的反相型式的至少一个反向散射回波(240、340、440、540);对所述编码脉冲的至少一个反向散射回波(220、320、420、520)和所述编码脉冲的反相型式的至少一个反向散射回波(240、340、440、540)进行相干求和(250、350、450、550);以及解码所述编码脉冲的反向散射回波(220、320、420、520)和所述编码脉冲的反相型式的反向散射回波(230、330、430、530),其中,所述解码通过以下自然发生:A. 至少所述编码脉冲(210、310、410、510)和所述编码脉冲的反相型式(240、340、440、540)在组织内的传播;以及B. 对于所述编码脉冲的反向散射回波(220、320、420、520)和所述编码脉冲的反相型式的反向散射回波(240、340、440、540)的所述相干求和(250、350、450、550)。 A match is not used and the compression decoding filter harmonic imaging method (200, 300), comprising the steps of: transmitting coded pulses greater than 1 of the time-bandwidth product of (210,310,410, Anti receiving said at least one coded pulse backscattered echo (220,320,420,520) and the encoded pulses; 510) and said encoder pulse inverting type (230,330,430,530) with at least one type of backscattered echo (240,340,440,540); said at least one coded pulse backscattered echo (220,320,420,520) and the encoder pulse inverting At least one type of backscattered echo (240,340,440,540) coherently summed (250,350,450,550); and decoding the encoded pulses backscattered echo (220,320,420 , 520) and said inverting type encoded pulses backscattered echo (230,330,430,530), wherein said decoding by naturally occurring: A at least the coded pulses (210, 310,. 410, 510) and inverting the encoder pulse pattern (240,340,440,540) spread within the organization; and B. For the coded pulse backscattered echo (220,320,420,520 above) and the coding type of inverted pulses backscattered echo (240,340,440,540) coherent summation (250,350,450,550).
2. 根据权利要求1的方法,进一步包括:在所述相千求和(250、 350、 450、 550 )之前或之后,使用通过至少一个所选频率并阻塞至少一个其它频率的滤波器(28),来过滤所述编码脉冲的反向散射回波(220、 320、 420、 520 )和所述编码脉冲的反相型式的反向散射回波(240、 340、 440、 540 )。 2. A method according to claim 1, further comprising: summing said phase thousand (250, 350, 450, 550) before or after, through the use of at least one selected frequency and at least one other frequency blocking filter (28 ), to filter the coded pulse backscattered echo (220, 320, 420, 520) and the encoder pulse inverting type backscatter echoes (240, 340, 440, 540).
3. 根据权利要求2的方法,其中,所述滤波器(28)包括带通滤波器、 基带低通滤波器以及失配滤波器中的至少一个。 3. The method according to claim 2, wherein said filter (28) comprises a band pass filter, at least one of the baseband lowpass filter and the mismatched filter.
4. 根据权利要求l的方法,其中,至少所述编码脉沖(210、 310、 410、 510)包括具有大于80%的带宽的至少一个超宽带频率调制脉冲。 4. The method according to claim l, wherein at least the coded pulses (210, 310, 410, 510) comprising at least one ultra-wideband frequency modulation of pulses having a bandwidth greater than 80%.
5. 根据权利要求1的方法,其中,选择所述至少一个脉冲的中心频率, 使得生成具有落入探头(12、 705、 805、 905 )的预定带宽范围内的中心频率的二次谐波信号。 5. The method of the second harmonic signal within the predetermined bandwidth center frequency claim, wherein the center frequency of the at least one pulse, so that the falling generate a probe (805, 905 12, 705) .
6. —种用于提供组织的组织谐波成像的超声波装置(10 ),其使用自然解码的编码激励而不使用匹配解码和压缩滤波器,该装置包括:探头(12、 705、 805、 905 ),用于向组织中发射至少一个编码脉沖(210、310、 410、 510)和所述编码脉沖的反相型式(230、 330、 430、 530 ),响应从所述组织反向散射的所述编码脉冲的至少一个回波(220、 320、 420、 520 )和所述编码脉沖的反相型式的至少一个回波(240、 340、 440、 540 ),而生成至少一个接收信号;以及相千求和模块(26),用于对所述编码脉沖的至少一个反向散射回波(220、320、 420、 520 )和所述编码脉冲的反相型式的至少一个反向散射回波(240、340、 440、 540)进行相干求和,以形成至少一个相干和;其中通过下列方式自然地对所述编码脉沖的所述反向散射回波和所述编码脉沖的所述反相型式的所述反向散射回波解码:A. 所述编码脉冲和所述编码脉冲的反相型式在组织内的传播;以及B. 对于所述编码脉冲的所述反向散射回波和所述编码脉冲的所述反相型式的所述反向散射回波进行相干求和。 6. - kind of ultrasonic device (10) for providing an organization of tissue harmonic imaging, which uses natural decoded coded excitation without using a matching decoding and compression filter, the apparatus comprising: a probe (12, 705, 805, 905 ), for transmitting at least one encoder pulse (210, 310, 410, 510) and the reverse phase encoding pulse pattern (230 to tissue, 330, 430, 530), a response from the tissue of the backscattered at least one of said encoding pulse echo (220, 320, 420, 520) and at least one of said encoding pulse echo type inverter (240, 340, 440, 540), and generating at least one received signal; and phase one thousand summing module (26) for at least one of the coded pulse backscattered echo (220, 320, 420, 520) and the encoder pulse inverting at least one type of backscattered echo ( 240, 340, 440, 540) coherently summed to form at least one coherent and; which naturally on the reverse of the encoding pulse echo and said inverse scattering pattern of the coded pulses in the following ways the backscattered echo decoding:. A coding of the encoded pulses and the inverted pulse type spread within the organization; and B. For the coding of the pulse and the backscattered echo The encoder pulse of the inverted type of backscattered echo coherently summed.
7. 根据权利要求6的装置,进一步包括:滤波模块(28),至少耦合至所述相千求和模块(26 ),并用于通过至少一个所选频率并阻塞至少一个其它频率。 7. The apparatus according to claim 6, further comprising: a filter module (28), coupled to said phase of at least one thousand summation module (26), and is used by at least one of the selected frequencies and blocks at least one other frequency.
8. 根据权利要求6的装置,进一步包括:至少一个多线发射器(26), 用于沿波束路径和多个波束路径中的至少一个发射多个脉冲。 8. The apparatus according to claim 6, further comprising: at least one multi-wire transmitter (26) for the beam along the beam path and a plurality of paths at least one of the plurality of transmit pulses.
9. 根据权利要求6的装置,进一步包括:至少一个多线接收器(22), 用于沿一个波束路径或多个波束路径,接收发射脉冲的一个回波或多个回波。 9. The apparatus according to claim 6, further comprising: at least one multi-line receiver (22) for one path or more beams along the beam path, receiving or transmitting a plurality of echo pulse echo.
Description  translated from Chinese

利用自然解码的编码激励进行组织谐波成像的方法和装置 Method and apparatus for decoding coded excitation using natural tissue harmonic imaging performed

技术领域 Technical Field

本发明一般涉及一种使用超声波机器的成像。 The present invention relates generally to a machine using ultrasound imaging. 具体地讲,本发明涉及一种使用超声波机器的组织谐波成像。 In particular, the present invention relates to a tissue harmonic imaging ultrasound machine.

背景技术 Background

组织谐波成像是一种在超声波机器中使用的公知成像方法。 Tissue harmonic imaging is a well-known imaging method for use in ultrasonic machines. 此类成像始 Such imaging start

于基于人们感觉到需要改善声对比剂(acoustic contrast agents)的效力,其中反向散射信号具有丰富的谐波。 People feel the need to improve the sound-based contrast agent (acoustic contrast agents) the effectiveness of the backscattered signal which has a rich harmonic. 在引入到医疗实践中后,明显地不用引入对比也能够获得图像,并且这些图像证明在图像清晰度上有提高。 After introduction to the medical practice, apparently without the introduction of contrast images can be obtained, and these images on the proof image sharpness has been improved. 因此,组织谐波成像借此被确立为一种成像模式。 Thus, tissue harmonic imaging is thereby established as an imaging mode. 先前,在生成组织谐波成像时一般使用两种方法,这些方法包括单次触发(firing)带通滤波和多次触发脉沖/相位反转。 Previously, when generating tissue harmonic imaging generally use two methods, which include single trigger (firing) bandpass filtering and multiple trigger pulse / phase reversal.

在公知的单次触发方法中,通过对接收信号应用带通滤波器来提取谐波分量。 In the known one-shot method, the application of the received signal band-pass filter to extract harmonic components. 然而,使用带通滤波可能限制带宽。 However, the use of a band-pass filter can limit bandwidth. 例如,必须限制发射信号和带通滤波器的带宽,以分离基波谱和谐波带。 For example, it must limit the transmit signal and the bandpass filter bandwidth, in order to separate the fundamental and harmonic spectrum band. 必须选择滤波器截止区,表示谐波信号损失和基波镨污染之间的平衡。 You must select a filter cutoff, showing balance and fundamental harmonic signal loss praseodymium pollution. 探头带宽的限制将迫使人们使用变窄的发射基波带。 Probe bandwidth limitations will force people to use narrow band of the fundamental emission. 窄带宽可能需要延长发射脉沖和滤波器脉沖响应,这继而可能导致轴向分辨率(axialresolution)的下降。 Narrow bandwidth may be required to extend the filter impulse response and the transmit pulse, which in turn may lead to axial resolution (axialresolution) decreases.

使用1998年1月13日出版的美国专利第5,706,819号中公开的脉冲(相位)反转,已极大地克服了公知的单次触发带通滤波的局限性。 U.S. Patent No. 5,706,819 January 13, 1998, published in the public pulse (phase) inversion, has greatly overcome the well-known one-shot bandpass filtering limitations. 已知的反相方法使用两个或更多个连续脉沖,该两个或更多个连续脉沖沿相同的路径但具有相反的极性。 Inverting known method uses two or more consecutive pulses, the two or more consecutive pulses along the same path but with opposite polarity. 从这些触发产生的反向散射信号的相干和消除了奇次谐波(包括基波)同时保留了用于形成图像的偶次谐波(包括二次谐波)。 For forming an image while retaining the even harmonics (including second harmonic) from coherent and eliminate these triggers backscattered signals generated by odd harmonics (including the fundamental). 反相成像允许宽带脉冲,从而保持了谐波成像的空间分辨率。 Inverted imaging allows broadband pulse, thereby maintaining the harmonic imaging spatial resolution. 然而,对于规则脉冲来说,宽带意味着短的脉沖长度,这继而导致穿透力的损失,尤其是在谐波成像中,二次谐波信号比基波信号大约小20dB。 However, for the regular pulse, the broadband means short pulse lengths, which in turn leads to the loss of penetration, especially in harmonic imaging, second harmonic signal smaller than the fundamental signal is approximately 20dB. 另外,在反相的情况下,对 Further, in the case inverted, for

4于沿相同波束路径的两次或多次触发的需求降4氐了帧频。 4 on the beam along the same path twice or more times demand triggered a drop 4 Di frame rate.

以下这样做是有利的:具有与脉沖反转谐波成像相关联的分辨率,同时保持与单次触发谐波成^U目关联的帧频、穿透力和信噪比(还被称为"SNR")。 The following is advantageous to do so: a pulse inversion harmonic imaging associated with the resolution, while maintaining a single shot into a ^ U Head harmonics associated frame rate, penetration and signal to noise ratio (also known as "SNR"). 然而,可以预期几个主要的困难。 However, we can expect several major difficulties. 首先,获得足够的穿透力和改善的SNR同时保持良好的分辨率总是困难的。 First, get enough penetration and improved SNR while maintaining good resolution is always difficult. 对于基波成像,已经采用了具有高的时间带宽乘积的频率调制信号(例如线性调频脉冲(chirp))。 For fundamental imaging, it has been used a high frequency modulation signal having a time-bandwidth product (e.g., a chirp (chirp)). 这种方法在适当解码以避免显著的距离波瓣(rangelobe)并保持良好的轴向分辨率之后,利用与常规脉冲相同的带宽,可能导致更高的穿透力和改善的SNR。 This method is appropriate in order to avoid significant decoding distance lobes (rangelobe) and maintain good axial resolution after identical use with conventional pulse bandwidth may lead to higher penetration and improved SNR. 在2001年4 月10日出版的美国专利第6,213,947Bl号中,公开了使用被设计取得最高SNR的匹配滤波器用于频率/ "非线性相位"调制编码激励。 In U.S. Patent No. 6,213,947Bl 2001 年 4 月 10 issue, there is disclosed a use is designed to achieve the highest SNR matched filter for frequency / "nonlinear phase" modulated coded excitation. 解码滤波器可被用于具有非常高的采样频率的RF信号,或者使用复滤波系数解调的RF信号。 Decoding filter can be used with very high RF signal sampling frequency, or use complex filter coefficients demodulated RF signal.

在这两种情况下,解码滤波器非常巨大并且昂贵。 In both cases, the decoding filter very large and expensive. 成本问题阻止了当前大部分超声器材公司实施频率/非线性相位调制编码激励,即使是在其最高级的超声波机器中。 Cost prevented the implementation of most of the current frequency ultrasound equipment company / nonlinear phase modulation coded excitation, even in its most advanced ultrasound machine. 即使成本可以接受,具有匹配设计的解码滤波器也可能大部分时间不能如预期地工作,尤其对于谐波成像。 Even if the cost can be accepted, with a matching design most of the time decoding filter may not work as expected, especially for harmonic imaging. 这是因为以下事实:在谐波成像中,解压缩变得更困难,这是因为与基波相比,作为时间的函数,相位变化快了两倍,并且一般通过不同组织生成组织谐波的复杂性大大降低了匹配压缩滤波的有效性,而匹配压缩滤波总是基于理想情况而设计。 This is due to the fact that: in harmonic imaging, decompression becomes more difficult, because compared to the fundamental, as a function of time, phase changes twice as fast, and general tissue harmonic generation by different organizations complexity greatly reduced the effectiveness of the matching compression filter, and the filter is always based on compression match ideally designed. 结果,距离旁瓣电平可能非常高,这对于超声波成像的实际应用没有意义。 As a result, the range side lobe level can be very high, which for the practical application of ultrasound imaging does not make sense. 对于解码, 目的在于通过牺牲一些SNR来降低距离旁瓣电平的失配滤波器(与TX Misaridis和JA Jensen在论文"An Effective Coded Excitation Scheme Based on A Predistorted FM Signal And An Optimized Digital Filter"中公开的类似)可能有所帮助。 For decoding, it aims to reduce the SNR by sacrificing some distance side-lobe level of mismatch filter (with TX Misaridis and JA Jensen disclosed in the paper "An Effective Coded Excitation Scheme Based on A Predistorted FM Signal And An Optimized Digital Filter" in like) may be helpful.

谐波成#>中的另一个困难在于近场谐波性能。 Harmonic to #> Another difficulty lies in the near-field harmonic performance. 因为在传播过程中逐渐生成组织谐波信号,所以由于微泡(microbubble)的局部非线性,组织中的谐波信号不同。 Because gradually generate tissue harmonic signal in the communication process, so since the microbubbles (microbubble) local nonlinear harmonic signals of different tissues. 因此,对于非常近的场(例如小于大约2cm),就不能在组织中生成足够的谐波分量。 Thus, for the very near field (for example, less than about 2cm), it can not generate enough harmonic components in the organization. 一般地讲,这造成了模糊图像特性,其中尤其在甚高频情况下,由于过量增益的小二次谐波信号的饱和或者由于基波信号的泄露, 细线可能呈现为粗块。 Generally speaking, this resulted in a blurred image characteristics, which especially in the very high frequencies, due to saturation excess gain small second harmonic signal or due to leakage of the fundamental signal, thin lines may appear as rough blocks. 这种现象严重限制了利用高频探头在诸如小部分的近场结构和表面结构中应用谐波。 This phenomenon severely limits the use of high frequency transducers used in near-field structure and surface structure, such as a small part of the harmonics.

第三个困难在于帧频。 A third difficulty is that the frame rate. 反相技术一般牺牲帧频,这是因为每个波束位置 Reverse phase techniques generally sacrifice frame rate, this is because the position of each beam

5需要多次触发。 5 requires multiple trigger. 有几项专利公开了帧频提高技术,例如2002年8月20曰出版的美国专利6,436,046Bl和2000年5月23日出版的美国专利6,066,099,, 这些专利文件包括例如多线获取(多个接收波束与发射波束之一相关联)、反相矢量的空间相邻传输以及同时多线传输。 Several patents disclose increased frame rate technology, for example, US Patent 6,436,046Bl 2002 published on August 20, said, and the US Patent May 23, 2000 issue of 6,066,099 ,, these patent documents include, for example multi-line acquisition ( a plurality of receiving one beam associated with the transmit beam), inverting the vector space adjacent transmission and simultaneous multi-line transmission.

因此,需要以克服以上困难的方式提供整个视野内的高质量谐波成像能力。 Therefore, in order to overcome these difficulties harmonic imaging capabilities provide high quality throughout the field of view.

发明内容 DISCLOSURE

本发明的一种实施方式关于使用超声波机器的组织谐波成像。 An embodiment of the present invention on the use of tissue harmonic imaging ultrasound machine. 本发明的至少一种实施方式使用时间带宽乘积大于1的宽带(大于约80%的BW)编码激励发射信号进行谐波成像。 At least one embodiment of the present invention uses a time-bandwidth product is greater than broadband (greater than about 80% of BW) coded excitation transmit signals harmonic imaging. 至少一种实施方式采用脉冲反转以去除基波信号,并且进一步采用多线获取、空间相位交替以及多线发射方法中的至少一种(或者这些方法中两个或更多的结合),以避免如先前所提供的由于两次触发而引起的帧频下降。 At least one embodiment using pulse inversion to remove the fundamental signal, and further to obtain a multi-line, at least one (or two or more of these methods in combination), and multi-line spatial phase alternating transmitting method, to Avoid triggers such as frame rate drop caused due twice previously provided. 宽带发射信号提高了甚近场中的谐波成像性能,同时与使用规则脉冲(时间带宽乘积=1)的普通脉冲反转方法相比,增加了穿透力和SNR。 Wideband transmit signal to improve the very near field harmonic imaging performance while using regular pulse (time-bandwidth product = 1) compared to conventional pulse inversion method, increasing the penetration and SNR. 通过编码脉冲在组织内的传播以及脉沖反转,自然实现接收信号的解码。 By encoding and pulse inversion pulse propagation in the organization, naturally achieve decoding received signals.

可以预期,与单次触发带通滤波谐波成像方法相比,本发明的实施方式能够大大提高图4象分辨率,同时保持与单次触发谐波成像相同甚至更好的穿透力和SNR,其远远超出了规则脉冲反转谐波成像的穿透力。 It can be expected, compared with a single-shot bandpass filter harmonic imaging method embodiments of the present invention can greatly improve image resolution in Figure 4, while maintaining the same trigger harmonic imaging even better penetration single and SNR , which goes far beyond the regular pulse inversion harmonic imaging penetration.

还可以预期,本发明的实施方式采用多线获取、空间相位交替以及多线发射方法中的一个或多个(或者这些方法中两个或更多的结合)。 It is also contemplated, embodiment of the present invention to obtain a multi-line, multi-line spatial phase alternating transmit and process one or more (or two or more of these methods in combination). 结果,与单次触发带通滤波谐波成像相比,不需要牺牲帧频来得到高很多的分辨率,, As a result, compared with a single-shot bandpass filter harmonic imaging without sacrificing frame rate to get much higher resolution ,,

本发明的一种实施方式关于一种进行谐波成〗象的方法,不使用匹配解码和压缩滤波器。 An embodiment of the present invention relates to a harmonic way into〗 like, do not use the matching decoding and compression filter. 该实施方式的方法包括:发射具有大于大约1的时间带宽乘积的编码脉冲和所述编码脉冲的反相型式;以及接收所述编码脉冲的至少一个反向脊:射回波和所述编码脉沖的反相型式的至少一个反向散射回波。 The method embodiment includes: transmitter having a bandwidth greater than approximately a product of the type encoded pulses and inverted pulses of said encoder; and receiving at least one of said encoding pulse reverse ridges: shot pulse echo and the coding at least one backscattered echo of the inverted type. 至少 At least

进行相干求和。 Coherent summation.

本发明的另一种实施方式关于一种进行谐波成像的方法,使用超声波机器而不使用匹配解码和压缩滤波器。 Another embodiment of the present invention relates to a harmonic imaging method using ultrasound machine without using a matched decoding and compressing filter. 该实施方式的方法包括:沿发射波束路径发射具有大于大约1的时间带宽乘积的至少一个编码脉冲;以及沿发射波束路径的相对侧,接收发射的编码脉冲的至少两个反向散射回波。 The method embodiment includes: transmit beam along a path having a transmit bandwidth greater than approximately a product of at least one coded pulse; and the opposite side of the beam emitted along a path, receiving the encoded at least two transmitted pulses backscattered echoes. 该方法进一步包括:形成所述至少一个编码脉冲的至少一个反相型式;发射所述至少一个编码脉冲的至少一个反相型式;以及沿发射波束路径的相对侧,接收所述编码脉冲的至少一个反相型式的至少两个反向散射回波。 The method further comprising: forming at least one of the at least one coded pulse inverter type; transmitting said at least one of the at least one coded pulse inverter type; and the opposite side of the beam emitted along a path, receiving at least one of said encoding pulse inverting at least two types of backscatter echoes. 对所述编码脉冲 The encoded pulses

波进行相干求和。 Wave coherent summation.

本发明的另一种实施方式关于一种进行谐波成^f象的方法,使用超声波机器而不使用匹配解码和压缩滤波器。 Another embodiment of the present invention relates to a harmonic ^ f as a method, instead of using the ultrasound machine and compression decoding filter match. 该实施方式的方法包括:沿第一波束路径发射具有大于大约1的时间带宽乘积的至少一个编码脉冲;以及接收发射的编码脉沖的至少一个反向散射回波。 The method embodiment includes: transmitter having a bandwidth greater than approximately a product of at least one coded pulse along a first beam path; and receiving encoded pulses transmitted to at least one backscatter echo. 该方法进一步包括:形成所述至少一个编码脉沖的至少一个反相型式;沿第二波束路径发射所述至少一个编码脉沖的至少一个反相型式;以及接收所述编码脉沖的至少一个反相型式的至少一个反向散射回波。 The method further comprising: forming at least one of the at least one coded pulse inverter type; transmitting said at least one of the at least one coded pulse along a second beam path type inverter; and at least one inverter receiving the encoded pulse pattern At least one backscattered echo. 对编码脉冲的至少一个反向散射回波和编码脉沖的反相型式的至少一个反向散射回波进行相干求和,形成沿第三波束路径的至少一个接收回波,其中,第三波&洛径与第一和第二波束路径呈间隔关系。 Coding at least one pulse of backscatter echoes of coded pulses and inverting at least one type of backscattered echo coherently summed to form a beam along a path at least a third received echo, wherein the third wave & Los path with the first and second beam path in spaced relationship.

本发明的另一种实施方式关于一种进行谐波成像的方法,使用超声波机器而不使用匹配解码和压缩滤波器。 Another embodiment of the present invention relates to a harmonic imaging method using ultrasound machine without using a matched decoding and compressing filter. 该实施方式的方法包括:沿两个分离的波束路径同时发射具有大于大约1的时间带宽乘积的至少两个编码脉冲;以及接收这两个发射的编码脉冲的至少两个反向散射回波。 The method embodiment includes: two beams along separate paths simultaneously emit light having a bandwidth greater than approximately a product of at least two coded pulses; and receiving the two coded pulses transmitted to at least two backscattered echoes. 该方法进一步包括: 形成编码脉冲的至少两个反相型式;沿两条波束路径同时发射所述编码脉沖的两个反相型式;以及接收所述编码脉冲的两个反相型式的至少两个反向散射回波。 The method further comprising: forming at least two types of reverse phase encoding pulse; along two beam paths simultaneously transmitting the coded pulse inverter type two; and at least two of said encoding pulse received two inverting type backscatter echoes. 对所述编码脉沖的至少两个反向散射回波和所述编码脉冲的两个反相型式的至少两个反向散射回波进行相千求和,形成沿两条波束路径的至少两个合成回波。 The encoded pulses of at least two at least two backscattered echo of the coded pulse and two inverted type with thousands of backscattered echo summed to form a beam along two paths at least two synthetic echo.

上述方法的一种或多种实施方式可以进一步包括:使用滤波器进行滤波, 通过至少一个所选频率并阻塞一个或多个其它频率。 One or more embodiments of the above method may further comprise: filtering using a filter, through at least one selected frequency and blocking one or more other frequencies. 可以预期,在相干求和之前或之后进行这样的滤波。 It is contemplated that the coherent summation before or after such filtering. 一种或多种实施方式包括:解码所述反向散射回波的至少一个相干和,其中,通过在组织内传播一个或多个编码脉沖和所述编码脉冲的一个或多个反相型式,以及对所述编码脉沖的一个或多个反向散射回波和所述编码脉沖的反相型式的一个或多个反向散射回波进行相干求 One or more embodiments include: decoding the backscattered echo at least one coherent and where, through the dissemination of one or more coded pulses and the coded pulses in the organization of one or more of the inverter type, and one for one or more of the coded pulse backscattered echo of the coded pulse and the inverted type or more coherent backscatter echo request

7和,自然发生这样的解码。 7 and, naturally occurring such decoding. 其它实施方式可以包括:选择至少一个脉冲的中心频率,使得生成的二次谐波信号的中心频率落入探头的预定带宽范围内, Other embodiments may include: selecting at least one pulse of the center frequency, so that the center of the generated second harmonic frequency signal falls within a predetermined bandwidth of the probe,

本发明的一种实施方式包括一种超声波装置,使用自然解码的编码激励而不使用匹配解码和压缩滤波器来提供组织的组织谐波成像。 An embodiment of the present invention comprises an ultrasonic device, using natural decoded coded excitation without using a matching decoding and compression filters to provide tissue harmonic imaging organizations. 该实施方式的装置包括:探头,用于将至少一个编码脉冲和所迷编码脉冲的反相型式发射到组织中;响应从组织反向散射的所迷编码脉冲和所述编码脉沖的反相型式的至少一个回波,而生成至少一个接收信号。 Apparatus of this embodiment comprises: the probe for at least one coded pulse and the fans of the inverter type coded pulses transmitted to the organization; response organization backscattered from the fans and the encoder pulse encoder pulse inverting type at least one echo, and generating at least one received signal. 该装置进一步包括:相千求和模块,用于对所述编码脉沖的至少一个反向散射回波和所述编码脉冲的反相型式的反向散射回波中的一个进行相干求和,以形成至少一个相干和。 The apparatus further comprises: phase one thousand summing module for at least one of the coded pulse backscattered echo of the coded pulse and the inverted type of backscattered echo of a coherently summed to forming at least a coherent and.

至少一种实施方式的装置包括:滤波模块,耦合到至少一个相干求和模块,并用于通过至少一个所选频率并阻塞一个或多个其它频率。 At least one embodiment of the apparatus comprising: a filtering module, coupled to at least one coherent summation module, and is used by at least one selected frequency and blocking one or more other frequencies. 可以预期, 所述滤波模块可以包括带通滤波器、基带低通滤波器以及失配滤波器中的至少一个或其组合。 It is contemplated that the filter module may comprise a band pass filter, a baseband low pass filter and mismatched filter, or a combination of at least one.

附图说明 Brief Description

图1示出根据本发明特定实施方式的超声波机器的实施方式的方框图; 图2示出的流程图描述了根据本发明的特定实施方式,使用(与图1所 Figure 1 shows a block diagram of an embodiment of the present invention, the particular embodiment of an ultrasonic machine according to; Figure 2 shows a flow chart of a particular embodiment described in accordance with the present invention, the use of (Fig. 1

示类似的)超声波机器或设备来进行组织谐波成像的方法,其使用自然解码 Similar shown) ultrasound machines or equipment for tissue harmonic imaging method using natural decoded

的编码激励; Coded Excitation;

图3示出的流程图描述了根据本发明的特定实施方式,使用(与图1所示类似的)超声波机器或设备来进行组织谐波成像的另一种方法,其使用自然解码的编码激励; Figure 3 shows a flow chart depicts a specific embodiment of the present invention, the use of (similar to that shown in Fig. 1) ultrasound machine or device to another tissue harmonic imaging method, which uses natural decoded coded excitation ;

图4示出的流程图描述了根据本发明的特定实施方式,使用(与图1所示类似的)超声波机器或设备来进行组织谐波成像的另一种方法,其使用自然解码的编码激励; Figure 4 shows a flow chart depicts a specific embodiment of the present invention, the use of (similar to that shown in Fig. 1) ultrasound machine or device to another tissue harmonic imaging method, which uses natural decoded coded excitation ;

图5示出的流程图描述了根据本发明的特定实施方式,使用(与图i所示类似的)超声波机器或设备来进行组织谐波成像的另一种方法,其使用自然解码的编码激励; Figure 5 shows a flow chart depicts a specific embodiment of the present invention, the use of (similar to that shown in Fig. I) ultrasound machine or device to another tissue harmonic imaging method, which uses natural decoded coded excitation ;

图6示出根据本发明的特定实施方式所设计的发射波波谱的例子; Figure 6 shows an example of emission according to a particular embodiment of the present invention is designed wave spectrum;

图7示出的方框图描述了根据本发明的特定实施方式,用于发射波束的一种方法;图8示出的方框图描述了根据本发明的特定实施方式,用于发射波束的另一种方法; Figure 7 shows a block diagram of a method is described according to a particular embodiment of the present invention, for emitting beam; FIG. 8 shows a block diagram of another method is described according to a particular embodiment of the present invention, for transmitting the beam ;

图9示出的方框图描述了根据本发明的特定实施方式,用于发射波束的另一种方法;以及 Figure 9 shows a block diagram describes another method for transmitting the beam according to a specific embodiment of the present invention for; and

图IO示出才艮据本发明的特定实施方式,在发射过程中脉冲缩短的例子。 Figure IO shows only Burgundy according to particular embodiments of the present invention, during the launch pulse shortening example. 当结合附图阅读时,可以更好地理解上述发明内容以及随后对本发明特定实施方式的详细描述。 When read with the accompanying drawings, it will be better understood above summary and detailed description of subsequent specific embodiment of the present invention. 为了说明本发明的目的,在附图中示出了特定实施方式。 To illustrate the object of the present invention are shown in the drawings certain embodiments. 然而,应该理解本发明不限于附图中所示的结构与构造。 However, it should be understood that the invention is not limited to the figures shown in the structure and configuration.

具体实施方式 DETAILED DESCRIPTION

只是为了说明的目的,以下详细描述参照了超声波机器、装置或设备的特定实施方式。 For purposes of illustration only, the following detailed description with reference to the ultrasound machine, the particular embodiment of the device or equipment. 然而,应该理解本发明可以用于其它设备或成像系统。 However, it should be understood that the present invention may be used in other devices or imaging systems.

本发明的一个或多种实施方式试图解决先前针对现有组织谐波成像实现所讨论的三种困难:1)穿透力、SNR以及分辨率之间的折衷;2)近场谐波性能;以及3)随着用于更高分辨率的多次触发的帧频下降。 One or more embodiments of the present invention attempts to solve the three previously difficult to achieve the existing tissue harmonic imaging discussed: compromise 1) penetration, SNR and resolution between; 2) near-field harmonic performance; and 3) with multiple trigger for higher resolution frame rate drop. 本发明的实施方式使用频率调制编码激励脉冲结合脉冲反转来解决这些困难,其中,波形具有大于大约1的时间带宽乘积,以及大于约80%的带宽。 Embodiments of the invention are used in combination frequency modulation encoding pulse inversion excitation pulse to address these difficulties, wherein the waveform has a bandwidth greater than approximately a product, as well as greater than about 80% of the bandwidth. 可以预期,不使用昂责的匹配解码/压缩滤波器用于解码。 It is anticipated that the responsibility does not use expensive matched decoding / compression filter for decoding.

图1示出根据本发明实施方式的超声波装置、设备或机器,被标记为10„ 探头/变换器(probe/transducer) 12通过将电模拟信号变换为超声波能量,将一个或多个超声脉冲波(例如,编码脉冲和/或编码脉冲的反相型式)发射到对象(例如,活体组织)中。在至少一种实施方式中,探头/变换器12通过将超声波能量变换为电模拟信号,从对象接收一个或多个反向散射超声回波(例如,编码脉沖和/或编码脉冲的反相型式的回波)。 Figure 1 shows an embodiment of the present invention, an ultrasonic device, equipment or machinery, is marked as 10 "Probe / transducer (probe / transducer) 12 by the electrical analog signal into ultrasonic energy, one or more ultrasound pulse (for example, coded pulses and / or coded pulse inverting type) is transmitted to the object (eg, biopsy) In at least one embodiment, the probe / converter 12 by the ultrasonic energy is converted into electrical analog signals from one or more object receives ultrasonic echoes backscattered (e.g., coded pulses, and / or reverse phase encoding pulse echo type).

在至少一种实施方式中,超声波设备10包括耦合至探头/变换器12并至少与探头/变换器12通信的发射/接收开关14。 In at least one embodiment, the ultrasonic device 10 includes a coupling to the probe / converter 12 and at least launch probe / converter communication 12 / receive switch 14. 发射/接收开关14用于使超声波设备10和探头/变换器12能够在发射和接收模式之间进行切换。 Transmit / receive switch 14 for the ultrasonic device 10 and the probe / converter 12 can be between transmission and reception modes. 例如,使用该开关,使探头/变换器12能够适当地发射一个或多个超声脉冲波,并接收一个或多个反向散射回波。 For example, use this switch, the probe / converter 12 can transmit one or more ultrasound pulse properly and receiving one or more backscatter echoes.

示出至少一个多线/交替矢量发射设备或模块16,耦合至发射/接收开关14并至少与发射/接收开关14通信。 Shows at least one multi-line / vector alternately transmitting device or module 16, is coupled to a transmit / receive switch 14 and at least the transmit / receive switch 14 to communicate. 根据以下提供的本发明实施方式,发射器模块16用于沿一条或多条线路或波束路径发射一个或多个脉沖(包括脉冲和脉冲的反相型式两者)。 According to an embodiment of the present invention is provided below, the emitter module 16 is used for one or more lines along the beam path or transmit one or more pulses (includes inverters both types of pulses and pulse). 图1还示出至少耦合至发射器模块16和波形生成器20并与其通信的至少一个波形存储器18。 Figure 1 also shows at least coupled to the emitter module 16 and waveform generator 20 and communicate with the at least one waveform memory 18. 才艮据本发明的一种实施方式, 波形生成器20生成至少一个或多个超声脉冲波和所述脉冲波的一个或多个反相型式,在发射之前被保存并存储在波形存储器18中。 According to one embodiment of Burgundy was present invention, a waveform generator 20 generates at least one or more of one or more types of inverting the ultrasonic pulse wave and pulse wave is stored prior to transmission and stored in the waveform memory 18 .

本发明的至少一种实施方式包括至少耦合至发射/接收开关14并与发射/ 接收开关14通信的至少一个多线接收器22。 At least one embodiment of the present invention comprises at least coupled to a transmit / receive switch 14 and the transmit / receive switch 14 in communication at least one multi-line receiver 22. 根据以下提供的本发明实施方式,接收器22用于沿一条或多条线路或路径接收发射脉冲的一个或多个回波或回波波束(包括脉沖和脉沖的反相型式的回波)。 According to an embodiment of the present invention is provided below, a receiver 22 for one or more lines along the path to receive or transmit one or more pulses of beam echo or echoes (including pulses and echo pulses inverting type). 多线接收器22还被示出耦合至矢量存储器24并与矢量存储器24通信。 Multi-line receiver 22 is also shown coupled to a vector memory and vector memory and communications 24 24. 在该实施方式中,矢量存储器用于接收、保存并存储一个或多个回波(包括脉沖和脉冲的反相型式的一个或多个回波)。 In this embodiment, a vector memory for receiving, storing and saving one or more echo (including a pulse and the inverted pulse type or a plurality of echo).

相干求和4莫块或设备26被示出至少耦合至矢量存储器24并与矢量存储器24通信。 Mo coherent summing block 4 or device 26 is shown coupled to the at least vector memory and vector memory and communications 24 24. 如以下所提供的,模块或设备26用于对脉沖的至少一个反向散射回波和该脉冲的反相型式的至少一个反向散射回波进行相干求和。 As provided below, module or device 26 for at least one backscatter pulse echo and the pulse of the inverter type at least one backscattered echo coherently summed. 相干求和模块26被示出耦合至滤波模块或设备28 (例如带通滤波器)并与其通信,, 在本发明的一个或多种实施方式中,滤波模块28使用一个或多个滤波器,至 Coherent summation module coupled to the filtering module or device 28 (e.g., a bandpass filter) and communicate ,, In one or more embodiments of the present invention, the filter modules 28 using one or more filter 26 is shown, to

所述一个或多个滤波器通过所选频率并阻止其它频率。 The one or more filters through the selected frequency and blocking other frequencies. 应该理解,模块26与模块28可以互换位置,这样根据实现,过滤每个反向散射回波可以发生在相干求和之前。 It should be appreciated, the module 26 and the module 28 can be reversed, so that depending on the implementation, each filter backscattered echoes can occur prior to coherent summation. 还可预期,滤波模块28不使用匹配解码/解压缩滤波器来完成这种滤波。 It is also contemplated, filter module 28 is not used to match the decoding / decompression filter to accomplish this filtering. 还可预期,滤波模块28可以使用失配滤波器,用于改善距离旁瓣电平„ It is also contemplated, filter module 28 may use mismatched filter for improved side-lobe level distance "

图1还示出其它信号处理模块或设备30,其至少耦合至滤波模块28并与滤波模块28通信。 Figure 1 also shows the other signal processing modules or devices 30, at least 28, and is coupled to the filtering module 28 to communicate with the filter module. 可以预期,该其它信号处理模块或设备30用于提供或执行任何其它所需或希望的信号处理。 It is contemplated that the other signal processing modules or device 30 for providing signal processing or perform any other required or desired. 该其它信号处理模块或设备30被示出耦合至扫描转换设备32并与扫描转换设备32通信,扫描转换设备32进一步耦合至显示器34并与显示器34通信。 The other signal processing modules or devices 30 and 34 is shown communicatively coupled to the scan converter device 32 to communicate with the scan converter device 32, the scan converter 32 is further coupled to a display device 34 and the display. 在一种实施方式中,扫描转换设备32 In one embodiment, the scan conversion apparatus 32

用于提供扫描转换功能、色彩映射功能以及组织/液流鉴定功能,并且将數据格式化用于示出。 For providing scan conversion functions, color mapping functions and organization / flow identification function, and the data format for showing. 显示器34接受来自扫描转换设备32的数据,并且显示结果图像。 Display 34 accepts data from the scan converter device 32, and displays the resulting image.

10本发明的至少一种实施方式包括中央控制器或控制处理器50,其可以包括超声波机器10的主要中央处理器,连接到超声波机器10的各种其它组件。 10 at least one embodiment of the invention comprises a central controller or control processor 50, which may include a main central processor of the ultrasound machine 10, is connected to the ultrasound machine 10 are various other components. 中央控制器50执行用于各种成像和诊断模式的各种数据算法和功能。 The central controller 50 to perform various data algorithms and functions for various imaging and diagnostic modes. 在中央控制器50和超声波机器10的一个或多个组件之间可以传送数字数据与命令。 Between one or more components of the central controller 50 and the ultrasonic machine 10 can transmit digital data and commands. 可替换地,由中央控制器50执行的功能可以由多个处理器或其组合来执行„ 可替换地,中央控制器50的功能可以集成到单个PC后端。 Alternatively, the functions performed by the central controller 50 by a plurality of processors, or combinations thereof can be performed "Alternatively, the functions of the central controller 50 may be integrated into a single back-end PC.

虽然未示出,但可以预期,本发明的至少一种实施方式包括用户接口, 使得用户命令能够由操作员输入到超声波机器10。 Although not shown, it is contemplated that, at least one embodiment of the present invention includes a user interface, so that the user command can be input by the operator to the ultrasound machine 10. 这样的用户接口可以包括键盘、鼠标、开关、旋钮、按钮、跟踪球、脚踏板、用于输入话音命令的走克风和屏幕菜单以及其它设备。 Such a user interface may include a keyboard, mouse, switches, knobs, buttons, trackball, pedals, for inputting voice commands and on-screen menu to go grams of wind and other equipment.

本发明的至少一种实施方式使用具有相位反转的超宽带编码波形。 At least one embodiment of the present invention is the use of ultra-wideband waveform encoding having phase inversion. 这样的超宽带波形通过组织内的传播与相位反转来自然解码。 Such ultra-wideband waveform through the dissemination and phase inversion within the organization to natural decoding. 还可以预期,至少一个编码波形可以是线性或非线性频率调制信号。 It is also contemplated that at least one coded waveform can be linear or non-linear frequency modulated signal. 在至少一种实施方式中, 一个或多个编码波形可以是线性频率调制信号,以及一个或多个其它编码波形可以是非线性频率调制信号。 In at least one embodiment, one or more coding waveforms may be linear frequency modulation signal, and one or more other code waveform may be non-linear frequency modulated signal. 本发明的至少一种或多个实施方式解决了先前讨论的存在于已知组织谐波成像方法中的困难。 At least one or more embodiments of the present invention solves the previously discussed known to be present in the tissue harmonic imaging methods difficult.

本发明的至少一种实施方式使用发射波形设计。 At least one embodiment of the invention uses the transmitted waveform design. 在至少一种实施方式中, 发射波形设计包括大于1的时间带宽乘积, 一般具有大于大约80%的分数带宽(也称为"BW")。 In at least one embodiment, the transmitted waveform design includes a bandwidth greater than the time the product generally has greater than about 80% of fractional bandwidth (also referred to as "BW"). 在这种实施方式中,波形可能被幅度和频率调制。 In this embodiment, the waveform may be amplitude and frequency modulation. 例如, 可以用窗口函数的形式来应用幅度调制,诸如高斯遮蔽(Gaussian shading )。 For example, in the form of a window function applied amplitude modulation, such as Gaussian shield (Gaussian shading). 频率调制可以是线性(例如在线性调频脉沖中)或非线性的。 It may be a linear frequency modulation (e.g. linear chirp) or non-linear. 选择脉冲的中心频率,使得所生成的二次谐波信号的中心频率落入探头的-12dB带宽范围内。 Center frequency selection pulses generated so that the center frequency of the second harmonic signal of -12dB fall within the bandwidth of the probe. 本发明的实施方式使用频率调制编码激励脉沖结合脉冲反转,其中,波形具有大于大约1的时间带宽乘积以及大于大约80%的带宽。 Embodiments of the invention are used in combination frequency modulation encoding pulse inversion excitation pulse, wherein the waveform has a time greater than about 1 and a bandwidth greater than the product of about 80 percent of the bandwidth. 还可预期,根据实际应用的问题,波形的带宽可以不必大于80%。 It is also contemplated, according to the practical application of the problems, the bandwidth of the waveform may not necessarily be greater than 80%.

图2示出的高级流程图描述了根据本发明的特定实施方式,进行组织谐波成像的方法,概括地标识为200,其利用自然解码的编码激励(使用与图1 所示类似的超声波机器或设备)。 Figure 2 shows a high-level flow is described in accordance with certain embodiments of the present invention, be tissue harmonic imaging method, generally identified as 200, its use of natural decoded coded excitation (using ultrasound machine similar to that shown in Figure 1 or equipment). 在至少一种实施方式中,使用具体指定的波形(使用脉冲反转)来进行组织谐波成像。 In at least one embodiment, the use of specific designated waveform (using pulse inversion) to perform tissue harmonic imaging. 更具体地讲,方法200包括步骤210,步骤210包括发射具有大于大约1的时间带宽乘积的至少一个编码脉冲(例如具有大于大约80%的带宽的超宽带脉冲)。 More specifically, method 200 includes step 210, step 210 includes a transmitter having a bandwidth greater than approximately a product of at least one encoder pulse (e.g., greater than about 80 percent of the bandwidth of the ultra-wideband pulses). 步骤220包括(例如沿同一波束路径)接收编码脉沖的至少一个反向散射回波。 Step 220 includes (for example along the same beam path) received at least one coded pulse backscattered echo. 步骤230包括:(例如沿同一波束路径)发射编码脉沖的至少一个反相型式。 Step 230 includes :( e.g. along the same beam path) inverting at least one type of encoded transmit pulse. 步骤240包括:接收编码脉冲的反相型式的至少一个反向散射回波。 Step 240 comprises: receiving an encoded pulse inverting at least one type of backscattered echo. 在至少一种实施方式中,方法200进一步包括步骤250,该步骤包括:对编码脉冲的至少一个反向散射回波和编码脉冲的反相型式的至少一个反向散射回波进行相干求和,以形成至少一个相千和。 In at least one embodiment, method 200 further includes step 250, which step comprises: at least one of the encoding pulse and the backscattered echo pulse inverter type encoding at least one summed coherently backscatter echo, to form at least one phase Chiwa. 在至少一种实施方式中,可以预期,(例如^f吏用带通滤波器)过滤编码脉沖的至少一个反向散射回波和编码脉冲的反相型式的至少一个反向散射回波的相干和。 In at least one embodiment, it can be expected (eg ^ f Officials with the band-pass filter) filtering at least one coded pulse backscattered echo pulse of the inverter type and encoding at least one backscattered echo of coherent and. 在另一实施方式中,可以预期,在相千求和之前,过滤编码脉冲的反向散射回波和编码脉冲的反相型式的反向散射回波中的至少一个。 In another embodiment, it can be expected in the phase before thousands of summation, at least one filter coded pulse backscattered echo and coded pulses of inverted pattern of backscattered echo. 在至少一种实施方式中,至少编码脉沖包括频率线性调制脉冲和频率非线性调制脉冲中的至少一个。 In at least one embodiment, it comprises at least an encoder pulse frequency and linear frequency modulation pulse modulated pulse nonlinear least. 另外,编码脉冲可以被幅度调制或频率调制。 Further, the encoding pulse can be amplitude modulation or frequency modulation. 还可以预期,选择所述至少一个脉冲的中心频率,使得生成的二次谐波信号具有落入探头的预定带宽范围之内的中心频率。 It is also contemplated to select the center frequency of the at least one pulse, so that the generated second harmonic signal having a center frequency of the probe falls within a predetermined bandwidth range.

图3示出的流程图描述了根据本发明的特定实施方式,利用自然解码的编码激励(使用与图1所示类似的超声波机器或设备)来进行组织谐波成像的方法,概括地标识为300。 Figure 3 shows a flowchart depicts a specific embodiment of the present invention, the use of natural decoded coded excitation (shown in FIG using ultrasound machine or similar apparatus) to perform tissue harmonic imaging method, generally identified as 300. 在一种实施方式中,使用具体指定的波形(使用脉冲反转)来进行组织谐波成像。 In one embodiment, the use of specific designated waveform (using pulse inversion) to perform tissue harmonic imaging. 在至少一种实施方式中,方法300包括步骤310,步骤310包括:发射具有大于大约1的时间带宽乘积的至少一个编码脉沖(例如具有大于大约80%的带宽的超宽带脉沖)。 In at least one embodiment, method 300 includes step 310, step 310 includes: transmitting at least one encoder pulse having a bandwidth greater than approximately a product (e.g., greater than about 80 percent of the bandwidth of the ultra-wideband pulses). 步骤320包括:沿发射波束路径的相对侧(例如右侧和左侧)接收发射的编码脉沖的至少两个反向散射回波波束。 Step 320 comprises: transmit beam along opposite sides of the path (e.g., right and left) receiving coded pulses emitted at least two beams backscattered echoes.

步骤330包括:形成至少一个编码脉冲的至少一个反相型式,并发射至少一个编码脉冲的至少一个反相型式(例如沿同一发射波束路径)。 Step 330 comprises: forming at least one of the at least one pulse inverter type encoding, and transmitting at least one of the at least one reversed phase encoding pulse pattern (e.g., a beam emitted along the same path). 步骤340 包括:沿发射波束路径的相对侧(例如右侧与左侧)接收编码脉沖的至少一个反相型式的至少两个反向散射回波波束。 Step 340 comprises: transmit beam along opposite sides of the path (e.g., right and left) receiving at least one coded pulse inverting at least two types of echoes backscattered beam.

方法300进一步包括步骤350,该步骤包括:对编码脉沖的至少两个反 Method 300 further includes step 350, the step comprising: at least two anti-encoding pulse

千求和,以形成至少两个相干和。 One thousand summed to form at least two coherent and. 在至少一种实施方式中,可以预期,(例如使用带通滤波器)过滤编码脉冲的至少两个反向散射回波和编码脉沖的反相型式的至少两个反向弟:射回波的相干和。 In at least one embodiment, it can be expected (for example, using a band-pass filter) filtration coded pulses of at least two counter-inverting type Scattered and coded pulses of at least two reverse brother: radio echo Coherent and. 还可以预期,在相干求和之前,过 It is also contemplated, prior to coherent summation, over

12滤编码脉冲的至少两个反向散射回波波束和编码脉冲的反相型式的至少两个 At least two 12-pulse filter encoding at least two backscattered echo beams and coded pulses inverting type

反向散射回波波束。 Backscattered echo beams. 在至少一种实施方式中,方法300进一步包括:至少编码脉冲为频率线性调制脉冲和频率非线性调制脉冲,并且可以是幅度调制或频率调制的脉冲。 In at least one embodiment, method 300 further comprises: at least a linear encoder pulse frequency modulation and pulse frequency modulation pulse nonlinear, and may be amplitude modulation or frequency modulation pulse.

图4示出的流程困描述了才艮据本发明的特定实施方式,利用自然解码的编码激励(使用与图1所示类似的超声波机器或设备)进行组织谐波成像的方法,概括地标识为400。 4 shows a flow chart sleepy Burgundy It describes only certain embodiments of the present invention, the use of natural decoded coded excitation (Fig using ultrasound machine or device similar to 1) tissue harmonic imaging method, generally identified 400. 在一种实施方式中,使用具体指定的波形(使用脉冲反转)来进行组织谐波成像。 In one embodiment, the use of specific designated waveform (using pulse inversion) to perform tissue harmonic imaging. 在至少一种实施方式中,方法400包括步骤410,步骤410包括:沿第一波束路径发射具有大于大约1的时间带宽乘积的至少一个编码脉冲(例如具有大于大约80%的带宽的超宽带脉冲)。 In at least one embodiment, method 400 includes step 410, step 410 includes: transmitting at least one encoder pulse having a bandwidth greater than approximately a product along a first beam path (e.g., greater than about 80% of the bandwidth of UWB pulse ). 步骤420包括:(例如沿同一波束路径)接收发射的编码脉沖的至少一个反向散射回波波束。 Step 420 comprises, for example along the same beam path :() receiving encoded pulses transmitted to at least one beam backscattered echo.

方法400进一步包括步骤430,步骤430包括:形成至少一个编码脉沖的至少一个反相型式,并沿第二波束路径发射至少一个编码脉沖的至少一个反相型式(例如,第二波束路径与第一波束路径在空间上相邻或临近)。 The method 400 further comprises step 430, step 430 comprises: forming at least one of the at least one encoder pulse inverting type, and transmitting at least one of the at least one coded pulse along a second beam path inverting type (e.g., the first and the second beam path adjacent or near the beam path in space). 步骤440包括:接收编码脉冲的至少一个反相型式的至少一个反向散射回波波束。 Step 440 comprises: receiving at least one coded pulse inverting at least one type of backscattered echo beam.

在至少一种实施方式中,方法400包括步骤450,该步骤包括:对编码脉沖的至少一个反向散射回波波束和编码脉冲的反相型式的至少一个反向散射回波波束进行相千求和,以形成沿第三波束路径的接收回波波束。 In at least one embodiment, method 400 includes step 450, which step comprises: at least one beam backscatter echo pulses and encoding at least one type of inverted backscatter echo beam phase encoding pulse is seeking thousands and to form a third beam along the beam path of the received echo. 在一种实施方式中,第三波&洛径与第一和第二波束路径呈间隔关系(例如在相邻的第一和第二波束路径中间)。 In one embodiment, the third wave & Los path with the first and second beam path in spaced relation to (for example in the adjacent first and second beam path in the middle). 可以预期,在至少一种实施方式中,过滤(例如使用带通滤波器)接收的回波波束。 It is contemplated that in at least one embodiment, the filter (e.g., using a band-pass filter) received echo beam. 在另一实施方式中,在相干求和之前, 过滤编码脉沖的至少一个反向散射回波波束和编码脉冲的反相型式的至少一个反向散射回波波束。 In another embodiment, prior to coherent summation, filtered encoding at least one pulse beam backscatter echo pulses and encoding at least one type of inverted backscatter echo beam. 在至少一种实施方式中,方法400进一步包括:至少编码脉冲为频率线性调制脉冲和频率非线性调制脉沖,并且可以是幅度调制 In at least one embodiment, method 400 further comprises: at least a linear encoder pulse frequency modulation and pulse frequency modulation pulse nonlinear, and may be amplitude modulation

或频率调制的脉冲。 Or frequency modulated pulse.

图5示出的流程图描述了根据本发明的特定实施方式,利用自然解码的编码激励(使用与图1所示类似的超声波机器或设备)进行组织谐波成像的方法,概括地标识为500。 Figure 5 shows a flowchart of a particular embodiment described in accordance with the present invention, the use of natural decoded coded excitation (shown in FIG using ultrasound machine or similar equipment. 1) tissue harmonic imaging method, generally identified as 500 . 在一种实施方式中,使用具体指定的波形(使用脉冲反转)来进行组织谐波成像。 In one embodiment, the use of specific designated waveform (using pulse inversion) to perform tissue harmonic imaging. 在至少一种实施方式中,方法500包括步骤510,步骤510包括:沿两个分离的波^J洛径同时发射具有大于大约1的 In at least one embodiment, method 500 includes step 510, step 510 includes: in two separate waves transmitted simultaneously ^ J Luo diameter of greater than about 1

13时间带宽乘积的至少两个编码脉冲(例如具有大于大约80%的带宽的超宽带脉冲)。 13 time-bandwidth product of at least two coded pulses (e.g., ultra-wideband pulse has greater than about 80% bandwidth). 这两个分离的波束路径相距足够远以避免声波串扰。 The two beams paths separated far enough apart to avoid acoustic crosstalk.

步骤520包括:(例如沿两个分离的波束路径)接收两个发射的编码脉冲的至少两个反向散射回波波束。 Step 520 includes :( e.g. a beam along two separate paths) receive two coded pulses emitted at least two beams backscattered echoes. 步骤530包括:形成编码脉沖的至少两个反相型式,并同时发射编码脉冲的两个反相型式(例如沿相同的两个波束路径)。 Step 530 comprises: forming at least two types of reverse phase encoding pulse, while two reverse phase encoding pulse emission type (e.g. two beams along the same path). 步骤540包括:接收编码脉沖的两个反相型式的至少两个反向散射回波波束(例如沿相同的两个分离波^J洛径)。 Step 540 comprises: receiving an encoded pulse two inverting at least two types of backscattered echo beam (for example, two separate waves along the same path Los ^ J).

在至少一种实施方式中,方法500包括步骤550,该步骤包括:对编码 In at least one embodiment, method 500 includes step 550, which step comprises: coding

个反向散射回波波束进行相干求和(以形成沿例如相同的两个波束路径的两个合成回波波束)。 A backscattered echo beams coherently summed (to form a synthetic echo for example, two beams along the same two beam paths). 在至少一种实施方式中,过滤(例如使用带通滤波器)这两个合成回波波束。 In at least one embodiment, the filter (e.g., using a bandpass filter), the two beams synthesized echo. 在另一实施方式中,在相干求和之前,过滤编码脉沖的 In another embodiment, prior to coherent summation, filtered coded pulses

波束。 Beam. 在至少一种实施方式中,对于每个编码脉沖,都形成所述编码脉沖的至少一个反相型式。 In at least one embodiment, for each encoder pulse, the encoder pulse is formed at least one type of inverter. 还可以预期,这两个波束路径在空间上分离。 It is also contemplated that the two beam paths are spatially separated.

图6示出具有相同时间长度和中心频率的超宽带脉冲和规则幅度调制脉冲的波谱的例子。 Figure 6 shows an example of having ultra-wideband pulse and pulse amplitude modulation rule of the same length of time and the spectrum of the center frequency. 示出了根据本发明特定实施方式的超宽带设计的发射波谱(图6中标记为610的实线)。 Shows a particular embodiment of the present invention, the design of ultra-wideband emission spectrum (Fig. 6 solid line labeled 610). 示出了规则脉沖波谱(示出为长短交替虛线, 标记为612),用于与超宽带的设计发射波语610进行比较,并且具有相同的时间长度。 It shows a regular pulse spectrum (shown as alternate long and short dashed line, labeled 612), and for the design of ultra-wideband speech transmission wave 610 is compared, and have the same length of time. 标记为614的虚线表示探头的带宽。 The dashed line labeled 614 probe bandwidths.

在至少一种实施方式中,使用了两次触发(即脉冲反转)。 In at least one embodiment, the use of two trigger (ie pulse inversion). 在这种情况下, 帧频下降成为严重的问题。 In this case, the frame rate drops become a serious problem. 图7-9中示出了本发明所使用的处理帧频下降的三种不同的实施方式。 Figure 7-9 shows the processing frame rate of decline in the present invention three different embodiments.

图7示出使用多线获取的根据本发明的至少一种实施方式。 Figure 7 illustrates the use of multi-line access to at least one embodiment of the present invention. 标记为700 的所示实施方式,每个发射波束使用多个(两个或更多)接收波束。 Labeled 700 in the embodiment shown, each using a plurality of transmit beams (two or more) receive beams. 图7示出探头705在左側和右侧具有两个波束(发射波束路径714左右側分别标记为710与712)。 Figure 7 shows a probe 705 having two left and right beams (left and right transmit beam path 714 side, respectively labeled 710 and 712). 可以预期,该实施方式可以将每帧的发射矢量减少一半或更多,从而达到与常规波束形成相同的接收线密度。 It is contemplated that this embodiment can reduce the transmission vector of each frame half or more, so as to achieve the same with the conventional beamforming reception line density. 结合多线获取和脉冲反转(其包括在正发射和负发射[反相]中接收多波束而非相应于一个波束的一个波束)有助于将帧频恢复到与常规单次触发谐波带通滤波相关联的帧频,同时保持脉冲反转谐波的优点。 Combined with multi-line acquisition and pulse inversion (which is included in the positive and negative emission emission [inverted] instead of receiving a multi-beam corresponding to a beam of a beam) helps the frame rate to return to the normal single-shot harmonics bandpass filter associated with the frame rate, while maintaining the advantages of pulse inversion harmonic. 图8示出本发明的另一实施方式。 Figure 8 shows another embodiment of the present invention. 该实施方式包括使用空间上的相位交替。 This embodiment includes the use of alternating phase space. 更具体地讲,该标记为800的实施方式包括探头805,该探头交替一个或多个波形的极性相位用于在空间发射矢量。 More specifically, the flag is the embodiment 805 comprises a probe 800, the probe or alternatively a polar phase for a plurality of waveforms in space launch vector. 更具体地讲,图8示出两个波形Tx (n)(具有正极性,被标记810)和Tx (n+l)(具有负极性,被标记812)。 More specifically, FIG. 8 shows two waveforms Tx (n) (having a positive polarity, labeled 810) and Tx (n + l) (having a negative polarity, labeled 812). 应该理解,虽然示出了两个波形,但是可以预期多于两个的波形。 It should be understood that although two waveforms is shown, it is contemplated that more than two waveforms. 另外,可以预期Tx (n) 810可以具有负极性,而Tx (n+l ) 812可具有正极性。 Further, it is contemplated Tx (n) 810 may have negative polarity, and Tx (n + l) 812 may have a positive polarity. 在至少一种实施方式中,可以通过在帧上平均执行两波束相千来抵消基波频率分量。 In at least one embodiment, can be executed by an average of two thousand at the frame beam phase to offset the fundamental frequency component.

图9示出本发明的另一实施方式。 Figure 9 shows another embodiment of the present invention. 该实施方式包括多线发射。 This embodiment includes a multi-line emission. 更具体地讲,标记为900的该实施方式与先前提供的图7所示的多线获取类似。 More specifically, it marked as 900 and the multi-line embodiment shown in FIG previously provided to obtain similar. 在该实施方式中,探头905在成像场中同时发射一个或多个分离的脉沖。 In this embodiment, the probe 905 simultaneously transmit one or more pulses separated in the imaging field. 在至少一种实施方式中,沿相同波M径(未示出)接收脉沖的反向散射回波,(例如使用滤波器)进行过滤并存储在存储器中。 In at least one embodiment, the receiving pulse wave M along the same path (not shown) backscatter echo (e.g., using a filter) was filtered and stored in a memory. 在所示实施方式中,在时间t, 发射两个分离的矢量,即,标记为910的Tx (n)和标记为912的Tx (n+k)。 In the illustrated embodiment, at time t, transmitting two separate vectors, i.e., labeled 910 Tx (n) and Tx 912 is marked as the (n + k). 反向书:射回波被接收、(例如使用带通滤波器)进行过滤,并且与存储的脉沖相干求和。 Reverse Books: radio echo is received (e.g., using a bandpass filter) was filtered, and the stored pulse coherent summing. 可以预期,使用本发明的至少一种实施方式,可以避免与脉冲反转相关联的帧频下降。 It is contemplated that the present invention is the use of at least one embodiment, can be avoided with the pulse inversion associated with the frame rate drop. Tx (n)和Tx (n+k)相距足够远以避免声波串扰。 Tx (n) and Tx (n + k) far enough apart to avoid acoustic crosstalk.

还可以预期,本发明的实施方式可以允许比单次触发带通滤波方法所能允许的帧频更快的帧频。 It is also contemplated embodiments of the present invention may allow more than one-shot band-pass filtering method allowed for the frame rate faster frame rate. 例如,前面所讨论的本发明的一种或多种实施方式可以结a来以提高帧频。 For example, one or more embodiments of the present invention previously discussed may be a junction to increase the frame rate. 例如,图7所示的多线获取实施方式可以与图9 所示的多线发射实施方式相结合,将帧频翻倍。 For example, multi-line shown in FIG. 7 embodiment can obtain a multi-line emission of the embodiment shown in Figure 9 combined, the frame rate doubling.

在本发明的至少一种实施方式中,具有大于大约80%的BW的脉冲的超宽带设计使得在发射脉冲中有更多的低频分量,从而显著提高了穿透力和SNR。 Ultra-wideband design at least one embodiment of the present invention, greater than about 80% of BW of pulses so that more low-frequency component in the transmitted pulse, thereby significantly improve the penetration and SNR. 声波衰减与频率成正比,其中对数衰减或者以dB表示的atten(r)可以 Sound attenuation is proportional to frequency, in which the number expressed in dB attenuation or atten (r) can

建模如下: atten(r)- 2 Modeling as follows: atten (r) - 2

其中,/表示频率,2表示往返路径,r表示传4番距离以及fl表示衰减系数。 Where / represents the frequency, 2 for the round-trip, r represents 4 Fan transfer distance and fl represent the attenuation coefficient. 因此,例如,在相同衰减的情况下,具有更低频率的脉沖能够穿透组织到更深的距离。 Thus, for example, in the case of the same attenuation, pulse having a lower frequency can penetrate into the deeper tissues distance. 增加低频分量以至少两种方式有助于穿透力:a)如上等式所示,可以取得更深的传输;以及b)因为所生成的二次谐波信号将具有落入探头的有效带宽内的波语,所以在接收側提高了SNR与穿透力。 Increasing the low frequency component in at least two ways contribute penetrating: a) As shown in equation, the transmission can be obtained deeper; and b) because the generated second harmonic signal having an effective bandwidth fall within the probe The wave language, so the receiving side to improve the SNR and penetration. SNR的提高 SNR improvement

15有助于对比分辨率。 15 helps contrast resolution.

与单次触发和规则脉冲反转方法相比,本发明的一种实施方式具有改善的图像分辨率(空间和对比度)。 Compared with the one-shot pulse inversion method and rules, an embodiment of the present invention has improved image resolution (spatial and contrast). 在至少一种实施方式中,采用脉冲反转以发 In at least one embodiment, the use of pulse inversion to send

射超宽带信号(大于大约80。/。的BW)。 Radio ultra-wideband signal (greater than about 80. /. The BW). 还可以预期,通过仔细设计时间带宽乘积,与单次触发带通滤波的情况相比,在谐波成像中点扩散函数将会更加紧密和平滑。 It is also contemplated by careful design time-bandwidth product, compared with a single-shot situation bandpass filtering, the mid-point spread function in the harmonic imaging will be closer and smoother. 另外,二次谐波信号中提高的SNR有助于克服基波信号泄露, 与规则脉沖反转相比,进而增加对比度和空间分辨率。 In addition, the second harmonic signal increased SNR help to overcome the fundamental signal leakage, compared with regular pulse inversion, thus increasing the contrast and spatial resolution.

最好超宽带发射在发射中包括更多的高频分量,从而允许近场谐波成像性能。 The best ultra-wideband transmitter included in the emission of high frequency components more, allowing the near-field harmonic imaging performance. 通过查看具有无损耗的二次谐波生成的组织中的谐波生成、来自单频源的平面波解(planewavesolution),可以理解该近场谐波成像性能。 Second harmonic generation of tissue by viewing with no loss of the harmonic generation, plane wave solutions (planewavesolution) from a single video source can be understood that the near-field harmonic imaging performance. 这种具有无损耗的二次谐波生成的组织中的谐波生成、来自单频源的平面波解可以由Hamilton MF 、 Blackstock DT.在爿co"幼cs,,中所公开的以下公式表示: This organization has a second harmonic generation lossless harmonic generation, plane wave solutions from a single video source can be represented by Hamilton MF, Blackstock DT following formula in valves co "Young cs ,, disclosed, he said:

We We

其中,P2表示二次谐波分量,x表示深度,p。 Wherein, P2 represents the second harmonic component, x represents the depth, p. 表示传播组织的密度,c 表示声速,p。 Density indicates the propagation organizations, c represents the speed of sound, p. 表示来源处的声压,P表示非线性系数以及co表示发射角频率., 根据上述等式可以看出,距离和频率的乘积(xco )与P2的强度成正比。 Represents the sound pressure at the source, P represents the nonlinear coefficient and emission indicates an angular frequency co., According to the above equation it can be seen, the product of distance and frequency (xco) proportional to the intensity P2. 因此,增加发射频率将导致在近场中更多的二次谐波生成。 Therefore, increasing the transmission frequency will lead to more second harmonic generation in the near field. 与变换器(即探头) 表面的距离越近,则需要更高的发射频率。 And transducer (probe) closer the surface, you need a higher transmission frequency.

本发明的一个或更多实施例仅^f吏用通过一个或多个所选频率而阻塞或阻止其它频率的滤波器,而不使用昂责的匹配解码和压缩滤波器。 One or more of the embodiments of the invention only ^ f officials with one or more selected frequency blocking filter or block other frequencies without using a matched decoding and compressing filter expensive responsibilities.

通过编码脉冲在组织内的传播和脉沖反转而自然发生解码。 Decoding occurs naturally spread by coded pulses and pulse inversion within the organization. 首先,在近场中,波形的低频部分产生非常小的谐波响应;仅高频部分产生显著的谐波回波。 First, in the near field, low frequency portion of the waveform generated very little harmonic response; only high-frequency part to generate significant harmonic echo. 这样,谐波信号的持续时间被缩短。 Thus, the harmonic signal duration is shortened. 使用脉冲反转来消除低频部分, 以及仅仅由高频部分产生的短持续时间的谐波信号对图像起作用。 Pulse inversion to eliminate low-frequency part, and the harmonic signals generated only by the short duration of the high frequency portion of the image function.

第二,在传输过程中,非常高的频率分量被衰减更快的衰耗掉,导致随着波穿过组织的传播而越来越短的脉冲。 Second, during transmission, very high frequency components are attenuated faster decline consume, resulting in wave propagation through tissue with more and more short pulses. 图IO示出超宽带信号在传输过程中变短(即袭减效应)的脉冲举例。 Figure IO shows surplus wideband signal during transmission shorter (ie hit minus effect) of pulses, for example. 该图示出由于高频分量的衰减,随深度增加脉沖持续时间变短。 The figure shows due to attenuation of high frequency components, with increasing depth the pulse duration is shorter. 这将有助于紧缩中场和远场区域中的点扩散函数。 This will help tighten the midfield and far-field region of the point spread function.

第三,相对于基波成像,谐波成像具有固有的紧缩和平滑点扩散函数。 Third, with respect to the fundamental imaging, harmonic imaging has inherent tightening and smoothing the point spread function.

16在基波成像中,设计编码激励波形以最大化穿透力。 16 in the fundamental imaging, coded excitation waveform designed to maximize penetration. 因此,编码激励技术(例如线性脉冲调频)通常采用非常长的发送波形和解码滤波器。 Therefore, coded excitation (such as linear pulse frequency modulation) usually very long transmission waveform and decode filter. 然而,在本发明的至少一种实施方式中,发送信号的编码激励波形不需要非常长,于是, 当与脉冲反转以及上述效应结合时,不需要解码。 However, in at least one embodiment of the invention, the coded excitation waveform is not required to send a signal very long, so, when the pulse inversion and a combination of these effects is not necessary to decode. 然而,应当理解,尽管不需要解码,用于改善距离旁瓣电平的设计仍然可被应用于接收的回波。 However, it should be understood that although decoding is not required, for improving the side lobe level from the design can still be applied to the received echo. 这里, Here,

失配滤波器不同于匹配滤波器,因为它不从最大化SNR的观点来匹配发送码。 Unlike mismatch filter matched filter, because it does not maximize the SNR from the point of view to match the transmitted code.

概括而言,本发明的至少一种实施方式引入具有大于大约1的时间带宽乘积的宽带(大于大约80%的BW)编码激励发送信号用于谐波成像。 In general terms, at least one embodiment of the present invention is greater than approximately 1 having incorporated the wideband bandwidth product (greater than about 80% of BW) transmits excitation signals for coding harmonic imaging. 至少一种实施方式使用脉冲反转,以去除基波重叠效应,并且还使用多线获取、 空间相位交替以及多线发射方法中的至少一个(或者这些方法中两个或更多个的结合),以避免如先前所提供的那样由两次触发所引起的帧频下降。 Pulse inversion mode, to remove the fundamental wave overlapping effect, and also to obtain multi-line, multi-line spatial phase alternating transmitting method and at least one (or two or more of these methods in combination a) at least one embodiment to avoid as caused by the trigger twice the frame rate of decline previously provided. 宽带发射信号改善了甚近场中的谐波成像性能,同时与使用规则脉沖(时间带宽乘积-l)的普通脉冲反转方法相比,增加了穿透力和SNR。 Wideband transmit signal improves the very near field harmonic imaging performance while using regular pulse (time-bandwidth product -l) compared to conventional pulse inversion method, increasing the penetration and SNR. 通过组织内的传播和脉冲反转而自然实现接收信号的解码。 Through the dissemination and pulse inversion that occurs naturally within the organization to decode the received signal.

可以预期,与单次触发带通滤波谐波成像方法相比,本发明的实施方式能够大大提高图像分辨率,同时保持与单次触发谐波成像相同甚至更好的穿透力和SNR,其远远超出了规则脉冲反转谐波成像的穿透力。 Can be expected, compared with a single-shot bandpass filter harmonic imaging method embodiments of the present invention can greatly improve image resolution, while maintaining the same one-shot harmonic imaging even better penetration and SNR, its far beyond the regular pulse inversion harmonic imaging penetration.

还可以预期,本发明的实施方式使用多线获取、空间相位交替以及多线发射方法中的一个或多个(或者这些方法中两个或更多个的结合)。 It is also contemplated, embodiment of the present invention to obtain a multi-line, multi-line phase space, and alternately transmitting method of one or more (or two or more of these methods in a combination). 结果,与单次触发带通滤波谐波成像相比,不需要牺牲帧频来获得高很多的分辨率。 As a result, compared with a single-shot bandpass filter harmonic imaging without sacrificing frame rate to achieve a much higher resolution.

本发明的另一实施方式将超宽带波形、相位反转和组织衰减相结合,这导致了接收谐波信号的自然压缩,得益于用于改善近场谐波成像性能的编码激励、更好的SNR和更强的穿透力,从而避免了对于昂贵的解码滤波器的需求。 Another embodiment of the present invention ultra wideband waveform, phase inversion and tissue attenuation combined, resulting in a natural harmonic signal compression received, thanks to incentives for improving coding near-field harmonic imaging performance, better SNR and better penetration, thus avoiding the need for expensive decoding filter needs.

虽然针对特定实施方式描述了本发明,但是本领域技术人员应该理解在不脱离本发明范围的前提下可以进行各种修改与等价物替换。 While the invention has been described for a particular embodiment, those skilled in the art will appreciate without departing from the scope of the invention various modifications may be provided with equivalent replacement. 另外,根据本发明的教导,在不脱离其范围的前提下,可以进行各种修改,以适应特定环境或材料。 In addition, according to the teachings of the present invention without departing from the scope thereof, can make various modifications to adapt a particular situation or material. 因此,本发明不限于所公开的特定实施方式,而是包括所有落入权利要求范围内的实施方式。 Accordingly, the present invention is not limited to the particular embodiment disclosed, but encompasses all embodiments falling within the scope of the claims.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US605094731 Dec 199818 Apr 2000General Electric CompanyMethod and apparatus for harmonic tissue imaging and contrast imaging using coded transmission
US624167431 Mar 19995 Jun 2001Acuson CorporationMedical ultrasound diagnostic imaging method and system with nonlinear phase modulation pulse compression
US637561831 Jan 200023 Apr 2002General Electric CompanyEnhanced tissue-generated harmonic imaging using coded excitation
Classifications
International ClassificationG01S15/89, G01S7/52, A61B8/00
Cooperative ClassificationG01S7/52038, G01S7/52095, G01S15/8959, G01S15/8963, G01S7/52093
European ClassificationG01S7/52S14F, G01S15/89D4D, G01S7/52S14D4, G01S7/52S2F1, G01S15/89D4
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