WO2015170183A3 - Method and apparatus for image scoring and analysis - Google Patents

Method and apparatus for image scoring and analysis Download PDF

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Publication number
WO2015170183A3
WO2015170183A3 PCT/IB2015/001374 IB2015001374W WO2015170183A3 WO 2015170183 A3 WO2015170183 A3 WO 2015170183A3 IB 2015001374 W IB2015001374 W IB 2015001374W WO 2015170183 A3 WO2015170183 A3 WO 2015170183A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
apparatuses
analysis
digital pathology
pathology images
Prior art date
Application number
PCT/IB2015/001374
Other languages
French (fr)
Other versions
WO2015170183A2 (en
Inventor
Rohit Jain
Kapil Dhingra
Edward HARTFORD
Original Assignee
Dako Denmark A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dako Denmark A/S filed Critical Dako Denmark A/S
Priority to EP15770634.2A priority Critical patent/EP3140778B1/en
Publication of WO2015170183A2 publication Critical patent/WO2015170183A2/en
Publication of WO2015170183A3 publication Critical patent/WO2015170183A3/en

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695—Preprocessing, e.g. image segmentation
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/24—Classification techniques
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/11—Region-based segmentation
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/194—Segmentation; Edge detection involving foreground-background segmentation

Abstract

Methods and apparatuses for analyzing digital pathology images are provided. The methods and apparatuses may provide estimates of staining intensity and proportion score in regions of interest within an image. Digital pathology images may be scored according to these metrics. The methods and apparatuses disclosed herein utilize various predetermined thresholds, parameters, and models to increase efficiency and permit accurate estimation of characteristics of a stained tissue sample.
PCT/IB2015/001374 2014-05-05 2015-05-01 Method and apparatus for image scoring and analysis WO2015170183A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP15770634.2A EP3140778B1 (en) 2014-05-05 2015-05-01 Method and apparatus for image scoring and analysis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461988566P 2014-05-05 2014-05-05
US61/988,566 2014-05-05

Publications (2)

Publication Number Publication Date
WO2015170183A2 WO2015170183A2 (en) 2015-11-12
WO2015170183A3 true WO2015170183A3 (en) 2016-01-07

Family

ID=54197001

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2015/001374 WO2015170183A2 (en) 2014-05-05 2015-05-01 Method and apparatus for image scoring and analysis

Country Status (3)

Country Link
US (1) US9852354B2 (en)
EP (1) EP3140778B1 (en)
WO (1) WO2015170183A2 (en)

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US9396532B2 (en) * 2012-11-15 2016-07-19 Siemens Healthcare Diagnostics, Inc. Cell feature-based automatic circulating tumor cell detection
CN105843555B (en) * 2016-03-18 2018-11-02 南京邮电大学 Spectrum hash method based on stochastic gradient descent in distributed storage
US11120069B2 (en) * 2016-07-21 2021-09-14 International Business Machines Corporation Graph-based online image queries
CN113164046A (en) * 2018-07-06 2021-07-23 恩真万特诊疗公司 Determination of tissue efficacy by quantitative tissue morphology analysis
CN109859217B (en) * 2019-02-20 2020-12-29 厦门美图之家科技有限公司 Segmentation method and computing device for pore region in face image
CN110060246B (en) * 2019-04-15 2021-08-24 上海商汤智能科技有限公司 Image processing method, device and storage medium
TWI732544B (en) * 2020-05-05 2021-07-01 國立中正大學 2d material thin film inspection method and 2d material thin film inspection system

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US5912165A (en) * 1993-08-18 1999-06-15 Applied Spectral Imaging Ltd Method for chromosome classification by decorrelaiton statistical analysis and hardware therefore
US20020186875A1 (en) * 2001-04-09 2002-12-12 Burmer Glenna C. Computer methods for image pattern recognition in organic material

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US7260248B2 (en) * 1999-12-15 2007-08-21 Medispectra, Inc. Image processing using measures of similarity
WO2004099773A1 (en) * 2003-04-30 2004-11-18 Pfizer Products Inc. Automated in vitro cellular imaging assays for micronuclei and other target objects
WO2006047502A2 (en) * 2004-10-25 2006-05-04 Brigham And Women's Hospital Automated segmentation, classification and tracking of cell nuclei in time-lapse microscopy
US8516029B1 (en) * 2008-06-12 2013-08-20 Carnegie Mellon University Methods and apparatuses for solving graph Laplacians
JP5387147B2 (en) * 2009-06-03 2014-01-15 日本電気株式会社 Pathological image diagnostic system, pathological image processing method, pathological image diagnostic program
WO2011044469A2 (en) * 2009-10-08 2011-04-14 Neodiagnostix, Inc. Diagnostic methods for oral cancer
US9970874B2 (en) * 2010-11-29 2018-05-15 Dako Denmark A/S Methods and systems for analyzing images of specimens processed by a programmable quantitative assay
US20130094750A1 (en) * 2011-10-12 2013-04-18 Tolga Tasdizen Methods and systems for segmentation of cells for an automated differential counting system
US8818030B2 (en) * 2011-12-13 2014-08-26 Xerox Corporation Post-processing a multi-spectral image for enhanced object identification
GB201200178D0 (en) * 2012-01-06 2012-02-22 Cytosystems Ltd Diagnostic method and system
CA2872722C (en) * 2012-05-11 2020-10-06 Dako Denmark A/S Method and apparatus for image scoring and analysis
US9412162B2 (en) * 2013-08-21 2016-08-09 Sectra Ab Methods, systems and circuits for generating magnification-dependent images suitable for whole slide images

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912165A (en) * 1993-08-18 1999-06-15 Applied Spectral Imaging Ltd Method for chromosome classification by decorrelaiton statistical analysis and hardware therefore
US20020186875A1 (en) * 2001-04-09 2002-12-12 Burmer Glenna C. Computer methods for image pattern recognition in organic material

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
THIERRY PECOT ET AL: "Non parametric cell nuclei segmentation based on a tracking over depth from 3D fluorescence confocal images", BIOMEDICAL IMAGING (ISBI), 2012 9TH IEEE INTERNATIONAL SYMPOSIUM ON, IEEE, 2 May 2012 (2012-05-02), pages 170 - 173, XP032198969, ISBN: 978-1-4577-1857-1, DOI: 10.1109/ISBI.2012.6235511 *

Also Published As

Publication number Publication date
WO2015170183A2 (en) 2015-11-12
EP3140778B1 (en) 2020-04-15
EP3140778A2 (en) 2017-03-15
US9852354B2 (en) 2017-12-26
US20150317537A1 (en) 2015-11-05

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